Giants WR Dwayne Harris is out for the season, according to ESPN's Adam Schefter.

Related players: Roger Lewis, Tavarres King, Odell Beckham, Brandon Marshall, Sterling Shepard

Harris has a fractured foot. Pretty much buried on the depth chart, it's only fantasy noteworthy because of all the Giant injuries at the position. The team likely will be without Beckham, Marshall and Shepard heading into Week 6 leaving Lewis and King as the team's top-two the way it stands today.

Giants believe WR Sterling Shepard suffered sprained ankle similar to one he had in summer; more tests Monday, per source.

Related players: Odell Beckham, Brandon Marshall

Schefter added it could be two weeks before Shepard plays so it's a week-to-week situation. Compared to the injuries to Beckham and Marshall, it sounds like Shepard will be back sooner than later and will likely be the top target for Eli Manning, so he's probably worth grabbing as soon as possible.

The worst-case scenario might have arrived for the New York Giants.

With four minutes remaining in the fourth quarter, already down three of their top receivers due to injury, Odell Beckham Jr. landed awkwardly after attempting to catch a high slant pass and left the field in a trainer's cart.

Wincing in pain, Beckham covered his face as the cart left the field. The injury was to his left ankle, which was trapped against the ground on the play.

Related players: Sterling Shepard, Brandon Marshall

This didn't look good. ESPN is reporting Beckham is already headed for surgery. NFL Red Zone reported it's a broken fibula. His ankle got pinned and bent under him after getting tackled. The Giants lost their top-three WRs this game so their offense will have some major questions heading into next week. Owners should probably plan on not having Beckham long-term, possibly the rest of the season.

Odell Beckham dislocated his right index finger in the second quarter of the game and had it repaired on the sideline. He also left twice in the fourth quarter after tweaking the ankle he hurt in the preseason, but returned to the lineup each time.

“It’s good. I came down in kind of the same motion that injured it. But came out of it fine,” Beckham said, via ESPN.com. “At the moment, the pain that you go through right then and there … you’ll overcome it. Just at the time, it was something that scares you for a second. It’s the same motion that happened, so … I’ll be all right.”

Beckham missed the first game of the season as a result of the initial ankle injury. The fact that he returned on Sunday would seem to be a good sign, although it will be something to monitor as the week progresses, the story said.