Adam Schefter of ESPN reports 49ers TE George Kittle will not practice this week due to his knee injury but the team has not ruled him out for Week 2.

Kittle took a nasty low hit early in the game against Arizona and was quiet thereafter. It sounds like he is in some dicomfort if the team is ruling him out of practice for the week on Wednesday. Kittle's status will have to be monitored all the way up until kickoff Sunday. This has the looks of a questionable tag and game-time decision situation.

The already banged-up San Francisco 49ers pass-catching corps added even more uncertainty Sunday when tight end George Kittle suffered a sprained left knee in a loss to the Arizona Cardinals.

That injury could put Kittle's status for Week 2 against the New York Jets up in the air depending on how this week plays out, coach Kyle Shanahan said.

"We'll see how he comes in on Wednesday," Shanahan said. "He was a little sore today but we'll wait to see how he is on Wednesday to see if he's able to practice or be able to go this week. We know there will be some question."

Related players: Jordan Reed

The story said Kittle came up hobbling near the end of the first half after taking a hit from Cardinals safety Budda Baker. Kittle was able to walk to the sideline, where he was evaluated by medical staff before heading to the locker room early. But Kittle returned after halftime and seemed to make it through the game OK, though he had no catches and was not targeted in the final two quarters after posting four catches for 44 yards on five targets in the first half. Reed would be next up as the TE1 if Kittle can't go.

George Kittle began his postgame Zoom call by loudly declaring: “I feel fantastic. Fantastic. Not an issue at all.”

If there was an issue, it appeared to be with his left knee, which seemed to get hyperextended on a hit by safety Budda Baker just before halftime. Baker crashed into the knee just as Kittle descended after leaping for a high pass from Garoppolo. The tight end left the game and was examined on the bench and in the locker room by the team’s orthopedic surgeon but played throughout the second half.

“I know he went out with a lower leg injury,” Shanahan said. “They don’t get into specifics with me. At halftime, he told me he was good to go, so he returned. I’m sure we’ll find out a little bit more (Monday) morning when he comes in.”

Related players: Jordan Reed

Kittle wasn’t targeted at all after halftime and he finished with four catches for 44 yards. The team’s No. 2 tight end, Reed, finished with two catches for 12 yards. Kittle seems to be OK after coming back in the second half, but it's worth monitoring.

49ers TE George Kittle returned to practice on Wednesday after sitting out a few days with a hamstring injury.

Kittle reportedly looked good in his return to practice and should be ready to roll for Week 1 when the 49ers take on the Cardinals. He remains an elite fantasy option at tight end and could command a career-best target share this season with all of the injuries San Francisco is dealing with at wide receiver.

49ers TE George Kittle is not practicing Friday according to Eric Branch of the San Francisco Chronicle. Kittle had a "tight hamstring" after Wednesday's practice according to head coach Kyle Shanahan.

The soft tissue bug nabbed the arguable TE1 in 2020. The season is less than two weeks away and the 49ers cannot afford to lose Kittle for any amount of time. This is an important injury to fantasy players and the injury-riddled San Francisco offense.

San Francisco 49ers tight end George Kittle has signed a five year extension worth $75 million.

George Kittle has deservedly become the highest paid tight end in the NFL. While the full year to year breakdowns are not yet known, we have learned that the star tight end will receive an $18 million dollar signing bonus, and that the deal has $30 million in true guarantees. The injury guarantee is $40 million. The size of this contract appears to be quite the value for the 49ers given Kittle's age, role, and production. Kudos to both sides for being able to agree to a market altering deal during the uncertainty NFL teams and players are currently contending with.

The 49ers are reportedly making "healthy progress" in finalizing a long-term contract extension for star TE George Kittle.

Bolder reports suggest that Kittle and the 49ers have already agreed to the framework of a six-year extension to be announced on Friday. Kittle's extension should come as no surprise as the Iowa product has blossomed into one of the premier players in all of the NFL over his first three seasons in the league. Kittle combines excellent pass-catching ability with otherworldly blocking in the run game, making him an irreplaceable piece of Kyle Shanahan's diverse offensive scheme. Kittle is an elite TE1 for fantasy purposes and can be drafted in the second round.

As the 49ers and star tight end George Kittle continue to work toward a long-term contract extension, San Francisco GM John Lynch told KNBR that the club expects to see the 26-year-old report to training camp on time Tuesday as veterans go through their first round of COVID-19 testing.

Kittle is entering the final year of his rookie contract and the two sides have been discussing a deal that will keep him in the Bay Area beyond 2020, the story went on to say. More recently, reports have bubbled up to the surface that suggest Kittle could earn a contract that pays him $13 million annually, which would dwarf Austin Hooper's current AAV with the Browns of $10.5 million, which is the league-high at the position.