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Malik Nabers is still in concussion protocol and is OUT for Sunday for the Giants at Seahawks , per Brian Daboll.

Related Players: Wan'Dale Robinson, Darius Slayton, Jalin Hyatt

This is a brutal loss to the offense in what has been a fantastic rookie season for Nabers. The whole offense is essentially a stay-away, though Robinson should continue to be targeted in PPR leagues, but more of a deep WR3 in other formats.

Sean McDermott says on WGR550 that DT Ed Oliver, WR Khalil Shakir, DT Austin Johnson, and S Taylor Rapp are OUT for Sunday’s game

Related Players: Mack Hollins, Curtis Samuel, Keon Coleman, Dalton Kincaid

The receiving room behind Shakir has been mostly miserable through the first month of the season, though the rookie Coleman has looked pretty good in his limited role. None of them are particularly exciting, though Coleman can be used as a desperation Flex in a game that should see him with a high route participation.

Kincaid becomes a top-5 option at the tight end position.

The Chiefs place WR Rashee Rice on IR as he awaits more info; Giants WR Malik Nabers faces an uphill battle this week; Colts RB Jonathan Taylor (high-ankle) likely misses time.

Related Players: Trey Sermon, Tyler Goodson

Rapoport continues that "it's mild, though he is likely to miss some time," and it would "be a surprise" if we see him suit up in Week 5. Bad news ahead of a great matchup against this Jaguars team that seems to be circling the drain already. Fire Sermon up as a fringe RB2/3 if Taylor is forced to sit.

Texans RB Joe Mixon, who missed both practices thus far this week, is not expected to play Sunday. That means the duo of Cam Akers (4.1 yards per rush) and Dare Ogunbowale (game-winning TD) once again.

It seemed as if Mixon was trending toward playing in Week 5, but he and Dameon Pierce look like they're out. In that case, we're lining up for another Akers week, which would put him in the RB2 radar against a Bills defense that has been gashed by the run through the first month of the season.

Texans RB Joe Mixon did not practice again today due to his sprained ankle.

Related Players: Dare Ogunbowale, Dameon Pierce, Cam Akers

It seemed as if Mixon was trending toward playing in Week 5, but he and Pierce still look like they'll be questionable. In that case, we're lining up for another Akers week, which would put him in the RB2 radar against a Bills defense that has been gashed by the run through the first month of the season.

For the second straight day, Commanders RB Brian Robinson did not practice today due to a knee injury.

Related Players: Austin Ekeler, Jeremy McNichols

This coincides with Ekeler's progress in the concussion protocol, which could end up leading to a ton of work for the veteran back in Week 5. We'll keep an eye on this situation heading into Friday.

Chiefs now have placed wide receiver Rashee Rice on injured reserve, meaning he’s out a minimum of four games.

Related Players: Xavier Worthy, Mecole Hardman, Juju Smith-Schuster, Travis Kelce, Justin Watson

It may be tough to hold Rice on your bench for a month, but he needs to be held on to in most league sizes. Kelce and Worthy figure to get the biggest bump, but keep an eye on the usage of the other ancillary pieces here in Week 5.

Daboll said RB Devin Singletary (groin) won’t practice again. Sounds like Dru Phillips (calf) and Adoree’ Jackson (calf) will be limited today.

Related Players: Tyrone Tracy, Eric Gray, Dante Miller

It's anyone's guess what the pecking order would be in this backfield without Singletary, but Tracy could be in for some extra receiving usage regardless, with Malik Nabers trending toward missing Week 5. The offense might look like a mess this week, but Tracy might end up being an interesting Flex play during the first round of Byes.

I asked Colts RB Jonathan Taylor if he’ll practice today (didn’t answer but later said “no”) and what will tell him he’s ready (or not) for Sunday:

“What’s today? Thursday, Friday, Saturday — so we got 48, really 72, but really 48 hours, so continuing to take it day by day. …”

Related Players: Trey Sermon

In a follow up question Taylor mentioned that this ankle injury "isn't as bad as 2022", but that just means he doesn't expect to hit IR. Tomorrow's injury report will tell us a lot, but it's not trending in the right direction. Consider Sermon a fringe RB2/3 if JT ends up sitting out Week 5.

While Malik Nabers (concussion) seems like a longshot to be ready for Seattle, RB Devin Singletary (groin) told me he has a chance. Wednesday was the best he’s felt since the Cowboys game.

Big couple days of practice upcoming to see if he can make it for Sunday.

Related Players: Wan'Dale Robinson, Darius Slayton, Jalin Hyatt

This would be a brutal loss to the offense in what has been a fantastic rookie season for Nabers. The whole offense would essentially be a stay-away, though Robinson should continue to be targeted in PPR leagues.