Week 3 vs. Oakland Raiders
Dalvin Cook is just one of two running backs so far in 2019 to get 20 or more touches in the first two weeks of the season. In Week 1 he ran 21 times for 111 yards and in Week 2 he ran 20 times 154 yards (scoring three times). He even has five catches for 46 yards so far this year as well. Long story short: Cook is getting touches, and is making the most out of it.
On paper, this should be a tough matchup against Oakland. The Raiders are allowing the fifth-fewest fantasy points to backs in 2019. But in Week 2, Oakland gave up over 400 passing yards, so there wasn't really a need to run. Cook should be just fine and can be trusted as a must-start RB1.