49ers injury updates:
RB Matt Breida (ankle) is out
WR Dante Pettis (knee) is out
TE Garrett Celek is in concussion protocol
WR Marquise Goodwin (calf bruise) and CB K’Waun
Williams (knee) will be re-checked on Wednesday.

Related players: Jeff Wilson

Wilson should see a big workload with Breida out. The Niners play at the Rams in Week 17.

The 49ers have declared wide receiver Pierre Garcon (knee) as out for Week 14. Marquise Goodwin is expected to make his return.

Garcon's absence should keep Dante Pettis relevant in fantasy leagues for at least one more week. Without Garcon and Goodwin the last two weeks, Pettis has scored three times on his way 13.7 and 24.7 PPR points. He should maintain a big enough role to be a viable flex play in most leagues.

Coach Kyle Shanahan said Friday that wide receivers Pierre Garcon (knee) and Marquise Goodwin (personal) are both out this weekend.

Dante Pettis saw seven targets last week and six the week before as the 49ers receiving corps has been decimated by injury and Goodwin's continued missed games for personal reasons. Last week against the Buccaneers, Pettis racked up 77 yards and a score, totals he could repeat as the lone 49ers receiver whose name anybody knows. Consider him a WR3/4 with WR2 upside against the Seahawks.

The #49ers downgraded WR Marquise Goodwin to doubtful, as he was excused to address a personal matter.

Against the terribly poor Bucs defense, expect 49ers TE George Kittle to be the primary passing game weapon for the 49ers with Matt Breida also a threat out of the backfield for QB Nick Mullins. It's a juicy match-up for 49ers offensive players.