49ers RB Elijah Mitchell is expected the carry the load in Week 2 against the Eagles.

Not surprising after Mitchell rushed for over 100 yards last week against the Lions after Raheem Mostert went down with what turned out to be a season-ending knee injury. Trey Sermon and JaMycal Hasty will see some work, but it will be Mitchell in the lead role as the 49ers visit Philadelphia. Mitchell checks in at No. 23 in our half-PPR rankings.

49ers RB Trey Sermon will be active for Week 2 at the Philadelphia Eagles according to Matt Barrows The Athletic. Offensive coordinator Mike McDaniel said there was "an 'extra aggressiveness' from Sermon in practice this week in response to game day status against the Lions," according to Barrows.

Related Players: JaMycal Hasty, Elijah Mitchell

Sermon's workload is unknown but it is clear that three running backs could see work for the 49ers. Shanahanigans!

And with RB Raheem Mostert announcing today that he is out for the season with a knee injury he sustained vs. Detroit, the 49ers now are signing former Lions’ RB Kerryon Johnson to their practice squad, per his agent

Related players: Elijah Mitchell Trey Sermon, JaMycal Hasty

The news of Mostert now being out for the season is a huge blow to fantasy teams who took their shot he would be the team's RB1. After Mostert went out, it was Mitchell who carried 19 times for over 100 yards and a score. For now, he's the presumed starter as both he and Hasty beat out Sermon in camp, according to Kyle Shanahan. Sermon should still be owned and has draft capital in his favor, but he may not have much of a role in the short term. For now it looks like it's going to be Mitchell's job.

49ers RB Raheem Mostert has chipped cartilage in his knee.

Related players: Elijah Mitchell, JaMycal Hasty, Trey Sermon

Well that didn't take long. The injuries at RB for the 49ers continue. Mostert will go on IR and HC Kyle Shanahan said expectation is about eight weeks for Mostert to return according to Wagoner. Mike Clay would tweet that the pecking order for RBs right now is Mitchell, Hasty and Sermon, and you can expect Sermon to be active against the Eagles in Week 2. As we posted earlier today, Sermon was simply beat out by Mitchell and Hasty in camp according to Shanahan. It's been no secret the team has loved Mitchell who was selected in the later rounds, but Sermon is the back with the highest draft capital. Sermon is a very risky start until we see him make a move up the depth chart, so for now it's Mitchell.

Kyle Shanahan says that Elijah Mitchell and JaMycal Hasty simply beat out Trey Sermon in training camp/preseason.

Related players: Raheem Mostert

Those who play dynasty league probably weren't shocked to see Mitchell earn time after Mostert went out with an injury. There's been all kinds of positive news in terms of the 49ers and their love for his ability since he was drafted. Yes it was against the Lions, but Mitchell ran for 19-104-1 after Mostert left the game. The 9ers backfield situation is always one to watch and is usually filled with injuries making the situation a fluid one week-to-week. Mitchell should be a popular pickup on the wires this week, but if Mostert is out in Week 2, Sermon could get a chance to make his mark as well.