The Giants released a list of players ruled out for this week and Shepard was on it.
Fantasy Impact:
The Giants already lost Odell Beckham Jr. and Brandon Marshall to season-ending injuries, and they will now be without the services of Shepard for at least this week. That means all three of the Giants' top WRs are missing in Week 6. The team's depth chart at WR now consists of Roger Lewis, Tavarres King, Travis Rudolph, and Ed Eagan. In a neutral matchup versus the Broncos, Lewis is our highest ranked Giants WR, but it's most likely in your best interest to look elsewhere.