Week 13 vs. Indianapolis Colts
DeAndre Hopkins has had volatile production since rookie Will Levis took over for Ryan Tannehill at QB in Tennessee. Hopkins finished as the weekly WR2 when Levis debuted in Week 8, but since that game has logged weekly finishes of WR27, WR57, WR18, and then posted 3-49-0 on five targets in Week 12. Hopkins looks like he has a WR2 ceiling for fantasy with Levis under center, but he also carries a low floor in games where the Titans can establish a positive game script and pound the run with Derrick Henry. The Colts are a neutral matchup for opposing wideouts, so it's probably best to think of Hopkins as a volatile WR3 in fantasy this week.