Week 10 vs. Jacksonville Jaguars
Patrick Mahomes threw all over the Titans' defense last week, finishing with 446 yards, giving him two games in a row with 400 or more passing yards. He also ran for 63 yards, which is a career high for him. He scored twice (one pass, one rush), giving him his seventh multi-touchdown game this year. Mahomes is having yet another incredible season, averaging 325.6 passing yards with 2.7 touchdowns per game. He gets a favorable matchup against the Jaguars in Week 10 and he'll remain a must-start option at quarterback.