Cardinals QB Kyler Murray (ankle) and WR DeAndre Hopkins (hamstring) are practicing Wednesday, their first since being on bye.

Hopefully the additional week of rest helps get both on the field Week 13. Their matchup against Chicago is exploitable.

Kliff Kingsbury said he remains hopeful that Kyler Murray and DeAndre Hopkins will play Sunday.

The tweet added Kingsbury won't fully say if they will or won't play until he sees them moving around in practice this week. Murray and Hopkins have missed three games and now a Week 12 bye, so the hope is both are ready to go against the Bears in Week 13.

Cardinals WR DeAndre Hopkins (hamstring) will miss Week 11's game at Seattle, while QB Kyler Murray (ankle) will once again be a game-time decision.

Related Player: Colt McCoy

Murray's multiple practice appearances makes him more likely Week 11 than any point the past three weeks. Hopkins is clearly dealing with a more significant hamstring issue.

Cardinals QBs Kyler Murray (ankle) and Colt McCoy (pectoral strain) were spotted at practice Wednesday.

This is great news for the Cardinals. Murray's ankle has had two-plus weeks of rest and McCoy has already said he would play Week 11. The Cardinals offense is obviously more explosive with Murray, so his return to practice is by far the biggest positive mid-week for Arizona.

Kingsbury on Kyler Murray this week, "it's going to be close."

Related players: Colt McCoy

Not what fantasy owners want to hear, but early reports said it would be a 1-3 week injury for Murray and his ankle. While McCoy was banged up and couldn't finish an ugly Week 10 loss to the Panthers, we reported earlier today McCoy would be able to play in Week 11 against Seattle if Murray can't suit up. It's trending to be a game-time call once again.

Arizona Cardinals backup quarterback Colt McCoy reportedly suffered a pectoral strain in the team’s 34-10 loss to the Carolina Panthers on Sunday, per NFL Network’s Ian Rapoport, but should be healthy enough to play if starting signal caller Kyler Murray were forced to miss Week 11’s matchup against the Seattle Seahawks.

Related players: Chris Streveler

Of course, the Cardinals are hoping Murray can return in Week 11. When Murry got hurt, reports said the ankle injury could keep him out 1-3 weeks, and Murray missed his second-straight week in Week 10. Streveler came on in relief of McCoy this past week.

Cardinals QB Kyler Murray (ankle) will be a game-time decision Week 10 against the Carolina Panthers.

Related Player: Colt McCoy

If Murray feels good Saturday and ahead of the game Sunday, then wheels up. Be prepared to have a late-game sub available since the Cardinals play Sunday afternoon.

The Cardinals were without QB Kyler Murray (ankle), WRs DeAndre Hopkins (hamstring) and Rondale Moore (concussion/neck), and RB Chase Edmonds (ankle) at Wednesday's practice.

The Cardinals have two more practices to hope for the best.