Week 6 vs San Francisco 49ers
Brandin Cooks is fantasy's WR33 through five weeks, a far cry from his WR13 overall finish in 2018. At this same point last season, Cooks was just the WR23, so there's reason to hope for significant improvement going forward. Cooks' 14.9-yard aDOT is the highest among Rams wide receivers, making his routes the longest on-average to develop, which makes Cooks arguably the most adversely affected by the Rams' offensive line struggles.
The Rams face a 49ers defense that boasts both a fantastic pass rush and a secondary adept in coverage, so if you're looking to identify a week with breakout potential for Cooks, this probably isn't it. Cooks is seeing the lowest snap volume among Los Angeles' starting trio of wide receivers, and his target rate of 10.2% is also the lowest. Until both Goff and the Rams offensive line show marked improvement in their ability to be successful on deeper throws, it's hard to trust Cooks as anything more than a mid-range WR3.