Brandon Aiyuk (shoulder) will be, as expected, a game-time decision for 49ers-Giants on TNF, per John Lynch on KNBR

Related Players: Deebo Samuel, Jauan Jennings, Ronnie Bell

The 49ers rarely have their "Big Four" all on the field simultaneously, which is a shame because it's such a fun offense to watch when it's rolling. We can expect a slight uptick in target share for both George Kittle and Deebo Samuel, while it's also likely Christian McCaffrey will get a little more action as a receiver. Though Jauan Jennings had a couple of big plays in the team's Week 2 victory, it's not enough to consider him in fantasy outside of DFS Showdown slates.