Rookie WR Alec Pierce is one of a handful of players who have already been ruled out for Sunday's contest against the Jaguars.
Related Players: Parris Campbell, Ashton Dulin
Fantasy Impact:
Matt Ryan's debut performance as the Colts' quarterback was middle-of-the-road at best, though he did rack up 352 yards passing in the Week 1 overtime tie. Ashton Dulin is the most likely scenario to be the 1v1 replacement for Pierce, with Parris Campbell continuing to operate out of the slot on the majority of his snaps. Meanwhile, there's no signs pointing towards a drop in Michael Pittman's 28% target share.