The 49ers placed RB JaMycal Hasty (collarbone) and S Johnathan Cyprien (hamstring) on injured reserve. The team has 16 players currently on IR.

Related players: Jerick McKinnon, Raheem Mostert

McKinnon should see a bulk of the work going foward, especially with the other 49er RBs injured, and at least until Mostert is able to return.

49ers RB JaMycal Hasty has a broken collarbone.

Related players: Jerick McKinnon, Kyle Juszczyk, Austin Walter

Hasty was trending in the wrong direction over the last few weeks, and his injury means he can be dropped in typical leagues. With Raheem Mostert, Jeff Wilson and Tevin Coleman out, it should mean a big workload for McKinnon going forward, at least until Mostert is able to return. Fullback Juszczyk could get more involved and Walter is a name to keep an eye out for despite being at the bottom of the depth chart.

49ers coach Kyle Shanahan said RB Tevin Coleman will be out this week with knee injury.

Related players: Jerick McKinnon, JaMycal Hasty, Austin Walter

Not a surprise as Coleman left Week 8 early after just returning to the lineup. Sources say Walter will be promoted to the roster from the practice squad, but most of the work should go to Hasty and McKinnon on Thursday night against the Packers. With Jimmy Garoppolo and George Kittle also out, fantasy output may be hard to come by for 49er plays.

49ers RB Tevin Coleman left Sunday’s game against the Seahawks with a knee injury and was ruled out for the remainder of the game. It’s very unfortunate as he had just been activated from injured reserve. JaMycal Hasty took over as the lead back and has scored a touchdown, though Sunday has been pretty rough for the 49ers with Jimmy Garoppolo and George Kittle also limping off the field.

Wide receiver Deebo Samuel and running back Jeff Wilson Jr., both of whom played major roles in Sunday's 33-6 win against the New England Patriots, are expected to miss extended time, according to coach Kyle Shanahan.

Related players: Kendrick Bourne, Jerick McKinnon, JaMycal Hasty

Samuel is dealing with a left hamstring strain and will "most likely" miss this week's game at the Seattle Seahawks and next week's home contest against the Green Bay Packers, according to Shanahan. Wilson is the latest 49er to suffer a high left ankle sprain and is expected to go on injured reserve this week, which means he will have to miss at least the next three games, the story said. As we reported just a bit ago, Bourne looks like he'll take over for Samuel while McKinnon could jump back into a bigger role at RB. The 49ers said they purposely cut back on McKinnon's workload this past week (surprise fantasy owners) but it should mean he gets a bigger role this week. However, the rookie Hasty has looked good and could take some of the workload at RB.

Kyle Shanahan said that the 49ers were planning to rest Jerick McKinnon all along.

Related players: Jeff Wilson, JaMycal Hasty, Tevin Coleman

Would have been nice to know... McKinnon didn't get work until Wilson suffered what looked like a serious injury to his ankle. The reason the 9ers gave was it was due to his heavy workload in some games earlier this season. With Wilson's status up in the air, at best, for Week 8, McKinnon should be back in the picture along with the rookie Hasty. With Coleman on the verge of coming back, he could also enter the picture to make the backfield situation even more cloudy.

As everyone who watched the 49ers-Rams game could see, however, JaMycal Hasty was delivering more pop in the running game than McKinnon — especially on those stretch zone runs — which is why Hasty got all of the fourth-quarter carries.

Related players: Jerick McKinnon, Raheem Mostert

The author called McKinnon "fine" in the passing game but the story was part of a mailbag piece and the person asking the question expected McKinnon to be more of a force in that department. The story said he expects McKinnon to get the start, but based on everything else, Hasty looks like he should be picked up this week if he's still on your wire as Mostert is going to miss at least three weeks.