The Cardinals were without QB Kyler Murray (ankle), WRs DeAndre Hopkins (hamstring) and Rondale Moore (concussion/neck), and RB Chase Edmonds (ankle) at Wednesday's practice.

The Cardinals have two more practices to hope for the best.

DeAndre Hopkins is day-to-day with a hamstring injury, Kliff Kignsbury said.

A.J. Green is still in the COVID protocol and has to test out of that in order to play.

Related players: Christian Kirk, Rondale Moore

Hopkins missed Week 9 along with Kyler Murray but the Cards still came away with a division win over the 49ers. We may have to go through the same thing this week as far as Hopkins' status and the uncertainty goes. The Cards host the Panthers in a later afternoon game in Week 10.

Cardinals QB Kyler Murray and WR DeAndre Hopkins are both officially inactive for Sunday against the 49ers.

Colt McCoy gets the start for the Cardinals. There had been little optimism of either playing and the team just made it official. Tough spot on the road in a divisional game for the 7-1 Cardinals. The remaining inactives:

Arizona Cardinals inactives

QB Kyler Murray
WR DeAndre Hopkins
CB Kevin Peterson
RB Jonathan Ward
DB James Wiggins

Cardinals HC Kliff Kingsbury told reporters Friday that QB Kyler Murray (ankle) and WR DeAndre Hopkins (hamstring) are game-time decisions Week 9.

Best to have back-up options in case neither plays. Even if both do, there could be limitations.

Arizona Cardinals wide receiver DeAndre Hopkins will play tonight against the Green Bay Packers on Thursday Night Football.

Hopkins was listed as questionable for tonight's contest but is expected to play against Green Bay, barring any setbacks in pre-game warmups. The Cardinals star receiver has been playing through questionable tags and missed practices all season, so he should be good for his regular workload. Hopkins is our 12th ranked wide receiver for Week 8.

Cardinals WR DeAndre Hopkins (hamstring) is questionable for Thursday night against the Green Bay Packers.

On a short week it is no surprise that Hopkins sat out Wednesday and is on the injury report. Expect Hopkins to play against the Packers.

Monday’s report said that neither wide receiver DeAndre Hopkins (hamstring) nor defensive end J.J. Watt (shoulder) would have taken part in practice. Both players were listed as non-participants on Tuesday as well.

Just like Monday, the story went on to say there’s been no word of concern out of Arizona that either player is at risk of sitting out against the Packers on Thursday night. The team will issue injury designations on Wednesday that will provide further hint about their availability, the story said.

The Cardinals issued an estimated injury report on Monday that included players like wide receiver DeAndre Hopkins, defensive end J.J. Watt, and quarterback Kyler Murray.

Hopkins and Watt would not have practiced a day after helping the team to a 31-5 win over the Texans. Hopkins is listed with a hamstring injury while a shoulder issue led to Watt being on the list. Murray was a full go.

The good news is, according to the story, there’s been no sign of concern about the availability of any of the players for Thursday’s game against the Packers.

Arizona Cardinals wide receiver DeAndre Hopkins missed Thursday's practice due to an illness.

Hopkins is dealing with a non-COVID-related illness and has missed two straight practices for Arizona. D-Hop is one of the rare players who does not need to practice to be cleared and effective, so this situation may not get resolved until some time this weekend. Fantasy managers should expect him to play this weekend but will want to have a contingency option at the ready. Hopkins is currently our 10th ranked wide receiver for Week 6.

Arizona Cardinals wide receiver DeAndre Hopkins returned to practice on Thursday.

Hopkins missed practice all last week with the rib injury, so a practice on a Thursday is positive news for the receiver, even if it turns out to be in limited fashion. Hopkins may take some time before he rounds back into full form but remains a weekly touchdown threat in a powerhouse offense. With a tough matchup against the Rams on deck, he is our 19th ranked receiver for Week 4.