Texans RB Joe Mixon, who missed both practices thus far this week, is not expected to play Sunday. That means the duo of Cam Akers (4.1 yards per rush) and Dare Ogunbowale (game-winning TD) once again.
Fantasy Impact:
It seemed as if Mixon was trending toward playing in Week 5, but he and Dameon Pierce look like they're out. In that case, we're lining up for another Akers week, which would put him in the RB2 radar against a Bills defense that has been gashed by the run through the first month of the season.