49ers’ WR Brandon Aiyuk, listed as questionable for tonight’s game due to a shoulder injury, is not expected to play vs. the Giants.
Related Players: Deebo Samuel, Jauan Jennings, Ronnie Bell
The 49ers rarely have their "Big Four" all on the field simultaneously, which is a shame because it's such a fun offense to watch when it's rolling. We can expect a slight uptick in target share for both George Kittle and Deebo Samuel, while it's also likely Christian McCaffrey will get a little more action as a receiver. Though Jauan Jennings had a couple of big plays in the team's Week 2 victory, it's not enough to consider him in fantasy outside of DFS Showdown slates.