Sean McDermott said that WR Amari Cooper (wrist) and FB Reggie Gilliam (hip) will be questionable vs. the Colts.

Related Players: Khalil Shakir, Mack Hollins, Dalton Kincaid

Keon Coleman has already been declared Out (and will "probably" miss multiple weeks), so it would be quite the blow to the passing offense if Cooper misses as well. Shakir should be locked into WR2 slots in fantasy.

WR Amari Cooper, CB Christian Benford and FB Reggie Gilliam are all considered day-to-day, according to Bills head coach Sean McDermott.

It was a surprise that Cooper was inactive leading up to Week 9. Cooper did log limited sessions last week, so owners will want to pay close attention to this week's practice reports to see if Cooper can get in a full session. The good news for owners is Cooper and the Bills play an early Sunday game at the Colts, so owners should know in plenty of time to adjust their lineups based on Coopers game status.

Sunday night’s game was stopped for several minutes in the first half after Bills running back Damien Harris was injured on a short run.

Harris suffered a neck injury after being hit by Giants linebacker Bobby Okereke and he was loaded on a backboard before being taken off the field by an ambulance.

Related players: James Cook, Latavius Murray, Reggie Gilliam

Harris was able to flash a thumbs up before leaving the field and the Bills announced that he had movement in his arms and legs shortly after the injury.

Source: Bills TE Dawson Knox broke a bone in his hand.

Related players: Reggie Gilliam, Tommy Sweeney

The tweet went on to say Knox's timeline is to be determined, but the hope is he won’t miss much time, especially with the bye this week for the Bills. Knox actually threw a two-point conversion after he suffered the injury. Gilliam and Sweeney are next up on the depth chart but probably don't offer the fantasy production Knox has given this season. Keep an eye on Knox's status after the bye.

The Bills had one of their most wide-open snap shares among tight ends against Seattle. In most games, they’ve had one top tight end available who gets the majority of snaps. In Dawson Knox’s first game back Sunday from a calf injury and the Reserve/COVID-19 list, he finished slightly behind Tyler Kroft in snaps. Knox’s 24 reps were six shy of Kroft’s 30, but the more intriguing development was the uptick in usage for undrafted rookie Reggie Gilliam. Against Seattle, Gilliam had 13 snaps, his highest share of the season.

The story added some of Gilliam's snaps came on goal-line plays, but the Bills worked Gilliam into offensive formations more. Outside of Kroft’s touchdown, the position overall was a non-factor in the passing game. Kroft’s 1-yard touchdown catch was the only attempt to a tight end the whole game. Were the Bills searching for answers at a position that’s been a big disappointment this season? The snap counts will be something to track next week against Arizona, the story went on to say.