Kent Sommers, Cardinals excellent beat writer, had these thoughts following the win over the Eagles:
This victory gives the Cardinals the luxury of not rushing QB Kevin Kolb back on a sore toe. He hasn't practiced in two weeks. And he wasn't playing well when he was practicing.
Just a guess, but I bet Skelton starts in San Francisco with Kolb as the backup. Then Kolb makes his return at starter the following week, in St. Louis.
Fantasy Impact:
The 49ers pass defense ranks in the bottom half of the league so Skelton could rank in or near the QB2 for leagues that go that route.