Per Kyle Shanahan, 49ers RB Christian McCaffrey us going back on IR with his PCL injury.

Related players: Isaac Guerendo, Deebo Samuel, Jordan Mason

It’s a 6 week recovery time for CMC, the post went on to say. It's possible he could return if the Niners make a long playoff run, but for this fantasy season, McCaffrey is done. Sandler, in a separate post, mentioned that Mason will also go on IR with a high ankle sprain, leaving Guerendo as the assumed RB1. The Niners will have to make a move to bring in more running backs, but the team did trade up in the fourth round to pick Guerendo, so it's possible they give him a legit chance the rest of the season. He should be a popular pickup off the wire this week.

After the game, coach Kyle Shanahan said that, from this point forward, Jauan Jennings will be playing the high-profile X-receiver position that Brandon Aiyuk manned before his season-ending knee injury.

Related players: Deebo Samuel, Ricky Pearsall

Jennings responded with a team-high 93 receiving yards, including 36 yards after the catch, the story pointed out. His 13-yard catch-and-run at the end of the game set up the game-winning field goal. Pearsall, meanwhile, finished second on the team with 73 receiving yards. Jennings played a 58 snaps at WR to lead all the 49ers at the position. Samuel had 48 snaps and Pearsall 41.

Deebo Samuel will be day-to-day with an injury to his ribs and an oblique strain, Kyle Shanahan said.

He’ll be re-evaluated after the bye, the post went on to say. Hopefully Samuel will be good to go for Week 10. Several 49ers are expected back at that point so the bye week is coming at a great time for the team. The Niners will be an early Sunday game at Tampa Bay in Week 10.

John Lynch on KNBR said Jauan Jennings is doubtful with his groin injury this week.

Related Players: Deebo Samuel, Ricky Pearsall, Jacob Cowing, George Kittle

If Deebo is good to go, we can assume the 49ers will be heavily targeting himself and Kittle this week in a good matchup. This makes both huge assets to fantasy squads, and rookie Ricky Pearsall is an interesting deep-league play in his second career game.

According to multiple reports, Deebo Samuel has been discharged from the hospital. Samuel left Sunday’s loss to the Chiefs with an illness and went to the hospital later that night.

Related players: Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing

Head coach Kyle Shanahan said that Samuel had fluid in his lungs and described his condition as pneumonia. Shanahan said that the team will see how Samuel recovers over the coming days, but owners should probably have other plans in place, especially because the Niners are at home against the Cowboys on Sunday night.

The illness that sidelined Deebo Samuel yesterday is pneumonia. He's in the hospital.

Related players: Brandon Aiyuk, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, George Kittle

When the team realized Deebo had fluid in his lungs, he was sent to the hospital, Lombardi said in another post. Another beat writer, Nick Wagoner, reported Samuel was struggling to breathe which is why he wasn't in the game very long. Aiyuk is out for the season so the Niners now find themselves very thin at the WR position. There is no timetable for Samuel's return at this point. Reports say the team should get Jennings (hip) back in Week 8, but rookies like Pearsall and Cowing could very well be factors in the short term until Samuel is able to return.

Sources: 49ers WR Brandon Aiyuk suffered a season-ending knee injury on Sunday, tests confirmed.

Related players: Deebo Samuel, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, Trent Taylor, George Kittle, Christian McCaffrey

Anyone who held on to Jennings should be in good shape as he will likely slide in as the team's WR2 behind Deebo. Jennings didn't play in Week 7 because of a hip injury but the team is hoping to have in back for Week 8, according to reports. Pearsall was active for the first time and caught three balls for 21 yards. Cowing had two catches for 50 yards. Both rookies could be options behind Samuel, Kittle and likely Jennings, but may not be consistent fantasy producers. We reported McCaffrey is looking to return on Nov. 10 and it's possible he's counted on as a receiver more than a rusher once he's back.

49ers TE George Kittle (hamstring) is doubtful for Sunday vs. the Rams. WR Deebo Samuel (calf) is out as expected. DE Nick Bosa (rib) is questionable.

Related Players: Eric Saubert, Jake Tonges

This would be yet another blow to a 49ers offense that is reeling. Saubert doesn't need to be started in typical fantasy leagues, and Brock Purdy's fantasy outlook would also take another huge hit.

49ers coach Kyle Shanahan told reporters that WR Deebo Samuel has a calf strain and will miss a few weeks. Another star injury for the Niners.

Related players: Brandon Aiyuk, Ricky Pearsall, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing, George Kittle

It's a big blow to the Niners offense, which is already without Christian McCaffrey for an extended time. There was no mention on whether or not Deebo could end up on IR. Aiyuk should take over as the team's WR1, but who takes over as the WR2 is the bigger question. Kittle is likely next up after Aiyuk, which then leaves Jennings, Bell, Conley and Cowing at WR. Jennings is probably the leading candidate, but probably won't be a safe play in typical leagues. Cowing is a rookie who has stood out over the spring and summer and has been returning kicks, so it's possible he earns a bigger role with Deebo out.

The 49ers placed WR Ricky Pearsall on the reserve/non-football injury list after he suffered a gunshot wound in an attempted armed robbery over the weekend. Pearsall, the team's first-round pick, will miss at least the first four games.

Related players: Brandon Aiyuk, Deebo Samuel, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing

The loss of Pearsall opens up the 49ers WR3 spot. However, with Aiyuk, Samuel and George Kittle, the Niners WR3 isn't always fantasy relevant. Despite that, Cowing could still be a name to keep an eye on. The rookie has generated a lot of positive press through camp this summer. However, guys like Jennings, Bell and Conley could also earn time in that WR3 role.