After the game, coach Kyle Shanahan said that, from this point forward, Jauan Jennings will be playing the high-profile X-receiver position that Brandon Aiyuk manned before his season-ending knee injury.

Related players: Deebo Samuel, Ricky Pearsall

Jennings responded with a team-high 93 receiving yards, including 36 yards after the catch, the story pointed out. His 13-yard catch-and-run at the end of the game set up the game-winning field goal. Pearsall, meanwhile, finished second on the team with 73 receiving yards. Jennings played a 58 snaps at WR to lead all the 49ers at the position. Samuel had 48 snaps and Pearsall 41.

The illness that sidelined Deebo Samuel yesterday is pneumonia. He's in the hospital.

Related players: Brandon Aiyuk, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, George Kittle

When the team realized Deebo had fluid in his lungs, he was sent to the hospital, Lombardi said in another post. Another beat writer, Nick Wagoner, reported Samuel was struggling to breathe which is why he wasn't in the game very long. Aiyuk is out for the season so the Niners now find themselves very thin at the WR position. There is no timetable for Samuel's return at this point. Reports say the team should get Jennings (hip) back in Week 8, but rookies like Pearsall and Cowing could very well be factors in the short term until Samuel is able to return.

Sources: 49ers WR Brandon Aiyuk suffered a season-ending knee injury on Sunday, tests confirmed.

Related players: Deebo Samuel, Jauan Jennings, Ricky Pearsall, Chris Conley, Ronnie Bell, Jacob Cowing, Trent Taylor, George Kittle, Christian McCaffrey

Anyone who held on to Jennings should be in good shape as he will likely slide in as the team's WR2 behind Deebo. Jennings didn't play in Week 7 because of a hip injury but the team is hoping to have in back for Week 8, according to reports. Pearsall was active for the first time and caught three balls for 21 yards. Cowing had two catches for 50 yards. Both rookies could be options behind Samuel, Kittle and likely Jennings, but may not be consistent fantasy producers. We reported McCaffrey is looking to return on Nov. 10 and it's possible he's counted on as a receiver more than a rusher once he's back.

49ers head coach Kyle Shanahan told reporters WR Brandon Aiyuk is feared to have torn his ACL during Sunday’s game against the Chiefs.

Aiyuk took a hard hit to his knee and was carted off the field. The injuries continue to pile up for the 49ers. He had two catches for 23 yards before leaving the game. With their top three receivers out, the 49ers had rookies Ricky Pearsall and Jacob Cowing leading the charge on the outside. Jauan Jennings should return soon and will be a hot fantasy target if he is still on the waiver wire.

49ers WR Brandon Aiyuk left Sunday’s game against the Chiefs with a potentially significant knee injury.

Aiyuk was carted off the field after taking a big hit to his right knee. Deebo Samuel also left the game, meaning the 49ers are now currently without Aiyuk, Samuel and Jauan Jennings. They did just activate rookie Ricky Pearsall. The hope is the injury isn’t too serious but Aiyuk is going to miss a decent amount of time at the very least.

49ers coach Kyle Shanahan told reporters that WR Deebo Samuel has a calf strain and will miss a few weeks. Another star injury for the Niners.

Related players: Brandon Aiyuk, Ricky Pearsall, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing, George Kittle

It's a big blow to the Niners offense, which is already without Christian McCaffrey for an extended time. There was no mention on whether or not Deebo could end up on IR. Aiyuk should take over as the team's WR1, but who takes over as the WR2 is the bigger question. Kittle is likely next up after Aiyuk, which then leaves Jennings, Bell, Conley and Cowing at WR. Jennings is probably the leading candidate, but probably won't be a safe play in typical leagues. Cowing is a rookie who has stood out over the spring and summer and has been returning kicks, so it's possible he earns a bigger role with Deebo out.

The 49ers will have wide receiver Brandon Aiyuk and left tackle Trent Williams against the Jets on Monday night, but they will not have running back Christian McCaffrey.

Jordan Mason, Patrick Taylor and Isaac Guerendo are the available backs for the Niners.

Definitely a shocker and likely a big blow to fantasy owners. According to the story, McCaffrey said on Friday that he had no doubt he would play and there was plenty of optimism from head coach Kyle Shanahan and General Manager John Lynch as well. McCaffrey missed most of the summer with a calf injury and is listed with an Achilles issue as well, the story said. Mason had a great camp and seemed to get a lot of attention from coaches this summer, and likely should get a bulk of the workload tonight against the Jets. Hopefully CMC owners backed themselves up during drafts by nabbing Mason. If Mason is still on your wire, he's worth picking up for any team in case CMC's issues are longer term. Taylor and Guerendo could get work for the Niners as well - if you're in a pinch losing CMC. From the Jets side, Braelon Allen and Israel Abanikanda could see touches behind Breece Hall.

The 49ers placed WR Ricky Pearsall on the reserve/non-football injury list after he suffered a gunshot wound in an attempted armed robbery over the weekend. Pearsall, the team's first-round pick, will miss at least the first four games.

Related players: Brandon Aiyuk, Deebo Samuel, Jauan Jennings, Ronnie Bell, Chris Conley, Jacob Cowing

The loss of Pearsall opens up the 49ers WR3 spot. However, with Aiyuk, Samuel and George Kittle, the Niners WR3 isn't always fantasy relevant. Despite that, Cowing could still be a name to keep an eye on. The rookie has generated a lot of positive press through camp this summer. However, guys like Jennings, Bell and Conley could also earn time in that WR3 role.

The 49ers are not trading star WR Brandon Aiyuk — he’s staying in SF with a massive extension.

Aiyuk is getting a front-loaded 4-year deal worth $120M. And yes, Aiyuk will now practice.

Related Players: Deebo Samuel, George Kittle, Jauan Jennings

The sweat is over for fantasy managers, and those who grabbed Aiyuk in the 4th are feeling fantastic. The 49ers are set to be an incredible offense once again and Aiyuk should be an easy click in the 3rd round.

Kyle Shanahan is hopeful that Ricky Pearsall will be ready for Week 1 for 49ers.

Related Players: Deebo Samuel, Brandon Aiyuk, Jauan Jennings

With no movement yet —or possibly at all— on the Aiyuk front, it seems unlikely that the rookie will make much of a fantasy impact unless someone in the offense misses time. He's an interesting (very) late-round dart throw, but nothing more for now.